Protein methyl transferases play critical roles Scale in numerous regulatory pathways that underlie cancer development, progression and therapy-response.Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as extrinsic microenvironmental signaling pathw
The United Nations Force Intervention Brigade: Wither the SADC/ICGLR Synchronised Peace Support Efforts in the Eastern Democratic Republic of Congo Recurring Conflict?
From the time it deployed in the eastern DRC in 2013 up to the first quarter of 2016, arguably no much tangible progress has been made by the United Nations Force Intervention Brigade (UN FIB).The security situation in eastern Congo continues to be unstable.This instability has serious direct security threats and spillover effects on respective nei
Non-invasive rehabilitation of hypoplastic amelogenesis imperfecta of a 14-year-old child
Background: Amelogenesis imperfecta is a rare developmental disorder.This condition can be quantitative as the hypoplastic type or qualitative as the hypomineralized hypomatured type.Case Report: This is the first clinical reported case in a 14-year-old Libyan female.It describes the oral management of hypoplastic amelogenesis imperfecta using a no
Information Extraction Tool Text2ALM: From Narratives to Action Language System Descriptions
In this work we design a narrative understanding tool Text2ALM.This tool uses an action language ALM to perform inferences on complex interactions of events described in narratives.The methodology used to implement the Text2ALM system was originally outlined by Lierler, Inclezan, and Gelfond (2017) via a manual process of converting a narrative to