PRMT5 function and targeting in cancer

Protein methyl transferases play critical roles Scale in numerous regulatory pathways that underlie cancer development, progression and therapy-response.Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as extrinsic microenvironmental signaling pathw

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The United Nations Force Intervention Brigade: Wither the SADC/ICGLR Synchronised Peace Support Efforts in the Eastern Democratic Republic of Congo Recurring Conflict?

From the time it deployed in the eastern DRC in 2013 up to the first quarter of 2016, arguably no much tangible progress has been made by the United Nations Force Intervention Brigade (UN FIB).The security situation in eastern Congo continues to be unstable.This instability has serious direct security threats and spillover effects on respective nei

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